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KMID : 0383820090670060556
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Tuberculosis and Respiratory Diseases
2009 Volume.67 No. 6 p.556 ~ p.559
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A Case of Acute Eosinophilic Pneumonia Associated with Intramuscular Administration of Progesterone Following In Vitro Fertilization
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Park Sung-Keun
Choi Byoung-Ho
Chon Su-Yeon
Kim Yu-Jin
Kyung Sun-Young
Lee Sang-Pyo
Jeong Sung-Hwan
Park Jeong-Woong
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Abstract
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Acute eosinophilic pneumonia (AEP) is characterized by idiopathic acute febrile illness, diffuse pulmonary infiltration, severe hypoxemia, and pulmonary eosinophilia. We report a case of AEP associated with intramuscular administration of progesterone as luteal phase support after in vitro fertilization. A 33-year-old woman presented to our emergency room with tachypnea and hypoxemia, complaining of fever and cough for 4 days, and dyspnea for 2 days. The symptoms began 9 days after the first injection of progesterone. Chest radiograph showed bilateral infiltrates, located predominantly in the periphery of the lungs, with blunting of the costophrenic angle. Symptoms and chest radiograph dramatically improved after corticosteroid therapy and shifting the progesterone from an intramuscular form of administration to a vaginal form of administration.
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KEYWORD
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Pulmonary Eosinophilia, Progesterone, Eosinophilia
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